Metabolism & Liver Health

Choline supports normal liver function, and helps prevent fat accumulation in the liver by transporting fats for other uses in the body. Choline performs several important jobs inside the liver:

  • Exports Liver Fats: choline packages fats for transport and eventual conversion to energy
  • Maintains Cell Health: Choline helps maintain normal cell membrane integrity
  • Reduces Waste: Choline controls the accumulation of homocysteine, an oxidizer generated during normal cell metabolism


The liver’s role in processing fat is the foundation of its ability to protect the human body from chemical imbalances and metabolic malfunction.  Extensive research supports the critical role of choline in liver health, both in animals and in humans:

  • The highest choline intakes are associated with decreased risk of fatty liver
  • Low choline intakes by post-menopausal women who already have fatty liver increases the risk of progressively severe liver dysfunction
  • Fatty liver is associated with systemic inflammation and is thought to be one of the first markers of metabolic syndrome

Unfortunately, non-alcoholic fatty liver disease (NAFLD) is becoming a significant health problem.  According to the American Liver Foundation,  NAFLD can be difficult to diagnose and has no visible symptoms.  Despite this fact, up to 30% of the population currently suffer from NAFLD, which makes adequate choline intake even more critical for those individuals.  Click here for a link to a video with Dr. Karen Corbin in which she explains choline’s important contributions to liver health.